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National Nanomedicine Seminar - "Nanoparticles in Our Foods: Characteristics, Applications, Gastrointestinal Fate, and Toxicity"

 

David Julian McClements, Ph.D.
Distinguished Professor, Department of Food Science
University of Massachusetts, Amherst

 

National Nanomedicine Seminar - "Nanoparticles in Our Foods: Characteristics, Applications, Gastrointestinal Fate, and Toxicity"

Edible nanoparticles are increasingly being utilized by the food industry to enhance the nutritional attributes, safety, shelf life, appearance, and texture of foods. A wide range of inorganic (e.g., titanium dioxide, silicon dioxide, zinc oxide, and silver) and organic (e.g., lipid, protein, and carbohydrate) nanoparticles is being used in these applications, which vary in their composition, physical state, shape, dimensions, aggregation state, and surface charge.  There is concern from consumers, industry, and regulators about the potential risks associated with ingesting these food-grade nanoparticles.  Consequently, a great deal of research is focused on understanding the gastrointestinal fate of different kinds of food nanoparticles, as well as their potential for causing chronic or acute toxicity.  In this presentation, current knowledge about the potential gastrointestinal fate and toxicity of both organic and inorganic food nanoparticles is reviewed, with special emphasis on the lipid nanoparticles found in food-grade nanoemulsions.  In particular, the importance of taking into account the nature of the food matrix and gastrointestinal conditions on the properties of food nanoparticles is highlighted.  In the case of nanoemulsions, there are a number of potential risks associated with reducing the size of the lipid droplets that should be considered: alterations in the fate of bioactive agents within the gastrointestinal tract; enhancement of the bioavailability of undesirable hydrophobic substances in foods (such as pesticides and hormones); potential toxicity of some of the ingredients used in their fabrication (such as synthetic surfactants).

Friday, November 9 at 3:25pm

121 Snell Library

Event Type

Seminar

Departments

Bouvé College of Health Sciences, COS, Physics, COE, Chemical Engineering, Bioengineering

Website

http://www.cancurecancer.org

Sponsoring Organization

CaNCURE and Nanomedicine Academy Programs

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